Background:

This gene is a member of the regulatory factor X gene family, which encodes transcription factors that contain a highly-conserved winged helix DNA binding domain. The protein encoded by this gene is structurally related to regulatory factors X1, X3, X4, and X5. It is a transcriptional activator that can bind DNA as a monomer or as a heterodimer with other RFX family members. This protein can bind to cis elements in the promoter of the IL-5 receptor alpha gene.

Applications:

IHC

Name of antibody:

RFX2

Immunogen:

Synthesized peptide derived from internal of human RFX2.

Full name:

regulatory factor X, 2 (influences HLA class II expression)

Synonyms：

0

SwissProt:

P48378

IHC positive control:

Human lung carcinoma tissue

IHC Recommend dilution:

50-100